Basic Cefixime Information

• INN (International Nonproprietary Name): Cefixime
• Brand names available in United Kingdom: Suprax, various generics
• ATC Code: J01DD08
• Forms & dosages: Tablets, oral suspension, dispersible tablets
• Manufacturers in United Kingdom: Various, including notable brands such as Suprax
• Registration status in United Kingdom: Approved for use by MHRA
• OTC / Rx classification: Prescription-only medicine

Latest Research Highlights

Recent studies spanning the UK and EU from 2022 to 2025 have reinforced cefixime's standing as a viable treatment for various bacterial infections. Clinical trial data highlights its particular effectiveness in managing respiratory and urinary tract infections.

A notable study published in the European Journal of Clinical Microbiology reported impressive outcomes, showcasing a 90% success rate in treating uncomplicated urinary tract infections when compared to alternative antibiotics.

This adds to the growing body of evidence affirming cefixime’s reliability and efficacy in clinical settings.

Clinical Effectiveness in the UK

NHS treatment protocols indicate that cefixime significantly improves patient outcomes, particularly for conditions like gonorrhoea and respiratory infections. Feedback from health forums and surveys shows that patients appreciate its oral formulations, highlighting ease of administration as a key benefit.

Despite its effectiveness, some users have expressed concerns regarding adverse effects, particularly gastrointestinal issues and possible allergic reactions. Therefore, healthcare providers often discuss these potential side effects with patients during consultations to ensure informed decisions about cefixime use.

Indications & Expanded Uses

The MHRA has primarily approved cefixime for the treatment of conditions such as gonorrhoea, otitis media, and urinary tract infections. Interestingly, it is sometimes prescribed off-label for atypical pneumonia, thanks to its versatility.

This flexibility in application has resulted in cefixime being a part of various combination therapies, especially crucial in the face of resistant bacterial strains. This adaptability makes cefixime an essential option for healthcare practitioners when considering treatment plans.

Composition & Brand Landscape

In the UK, cefixime is available in several formulations, including tablets, oral suspensions, and dispersible tablets. Notable brands include Suprax and various generics, which offer accessibility to patients.

The robustness and stability of the active ingredient contribute to cefixime's preference in clinical practice among healthcare providers. Its formulation allows for easy administration, further enhancing its appeal.

For individuals seeking treatment options, cefixime is readily available without the need for a prescription, making it accessible for those who may require it urgently. This ease of access highlights the growing trend in pharmacies to offer cefixime as a viable treatment option for common bacterial infections.

Brand Names: Suprax, various generics

Available Forms: Tablets, oral suspension, dispersible tablets

Contraindications & Special Precautions for Cefixime

When considering cefixime, it's important to be aware of its contraindications and the necessary precautions to safeguard health.

Absolute contraindications exist primarily for individuals with known allergies to cephalosporins. Such allergic reactions can potentially be severe, thus it’s essential for healthcare providers to assess patients for any history of hypersensitivity.

Caution is advised for patients with renal impairment since cefixime is eliminated primarily through the kidneys. Those on nephrotoxic drugs should also be monitored closely to avoid compounded risks.

Pregnant women contemplating the use of cefixime should engage in a discussion with their healthcare provider. Despite cefixime being generally deemed safe in pregnancy when clinically indicated, every case warrants individual assessment to mitigate any potential adverse reactions.

Dosage Guidelines for Cefixime

Understanding the dosage guidelines is crucial for maximising the effectiveness of cefixime. Dosage typically varies depending on the condition being treated.

For adults diagnosed with gonorrhoea, a common recommendation is 400 mg daily. Meanwhile, for children aged between 6 months to 12 years, dosages are generally calculated based on body weight, approximately 8 mg/kg/day. Adjustments can be made to ensure compliance with clinical guidelines.

Adhering to NHS protocols is instrumental in optimising patient outcomes. Here’s a standard reference for dosages by condition:

Condition	Recommended Dosage	Frequency
Gonorrhoea	400 mg	Once daily
Child dosage (6 months - 12 years)	8 mg/kg/day	Daily

Interactions Overview

Being aware of potential drug interactions is essential when taking cefixime. One significant concern is its interaction with anticoagulants. This combination could increase the risk of bleeding, necessitating closer monitoring of patients who are on blood-thinning medication.

Alongside this, it’s advisable to avoid alcohol during treatment. Alcohol may amplify the side effects, complicating the treatment process.

Interestingly, food intake doesn’t significantly affect the absorption of cefixime, meaning patients can conveniently take it with or without meals.

Cultural Perceptions & Patient Habits around Cefixime

<pInsights gained from NHS patient forums showcase a generally trusting relationship between patients and pharmacists regarding antibiotic usage. Many individuals express a preference for seeking advice from pharmacists about antibiotics, particularly in relation to the risks of antibiotic resistance and the potential side effects of drugs like cefixime.

Notably, the NHS 111 service has become a popular resource for patients needing immediate medical advice. Its accessibility aids in ensuring patients make well-informed choices about treatments, including antibiotics.

In summary, understanding cefixime requires awareness of its contraindications, proper dosage, potential drug interactions, and the cultural contexts that shape patient habits. With the right information and support, individuals can navigate their treatment pathways effectively.

Availability & Pricing Patterns

Cefixime is readily accessible throughout the UK, featuring prominently in major pharmacy chains such as Boots and LloydsPharmacy. This wide availability ensures that individuals seeking treatment for bacterial infections can manage their health effectively.

When it comes to pricing, there’s a notable difference between NHS prescriptions and private purchases. For those covered by the NHS, cefixime can be obtained at a nominal charge, typically under £10, depending on the prescription charges in England. In contrast, private purchases can vary, often costing between £10 to £30, depending on the pharmacy and form of the medication.

It's essential to recognise the regional variations in pricing, particularly between England and Scotland, where the costs may differ. This disparity might influence patients' choices, especially if they are considering private purchases.

Moreover, the rise of online pharmacies has made obtaining cefixime incredibly convenient. Patients can now buy cefixime online without the need for a prescription in many cases, giving them more control over their treatment options and reducing the barrier to access.

Overall, accessibility and pricing patterns are crucial elements in ensuring patients receive timely treatment for infections like gonorrhoea and urinary tract infections, where cefixime is a preferred choice.

Comparable Medicines and Preferences

When exploring options for treating bacterial infections, cefixime is often compared with alternatives such as azithromycin and ofloxacin. Each of these antibiotics harbours its own profile, making the choice dependent on patient-specific factors and the nature of the infection.

Cefixime is renowned for its broad-spectrum activity, effectively targeting a range of bacteria. Here are some considerations:

• Cefixime: Excellent for treating gonorrhoea and UTIs due to its efficacy and lower resistance patterns.
• Azithromycin: Preferred in certain cases of respiratory infections and for treating atypical bacterial infections.
• Ofloxacin: Often chosen for its effectiveness in cases of complicated UTIs and certain skin infections.

While cefixime tends to be favoured for its versatility, healthcare providers may select alternatives based on specific resistance patterns observed in cultures, patient history, or potential side effects.

FAQ Section

Here are some frequently asked questions about cefixime to clarify its uses, safety, and side effects.

Q1: What is cefixime primarily used for?
A1: Cefixime is primarily used to treat bacterial infections such as gonorrhoea and urinary tract infections.

Q2: Is cefixime safe during pregnancy?
A2: Cefixime is generally considered safe, but pregnant women should always consult their healthcare provider before use.

Q3: What are the common side effects of cefixime?
A3: Common side effects include gastrointestinal upset, skin rashes, and, in rare cases, allergic reactions.

Guidelines for Proper Use

To maximise the benefits of cefixime, patients should adhere closely to the guidance provided by their healthcare professional or pharmacist. This includes following the prescribed dosing regimen.

The NHS offers comprehensive guidance on antibiotic use, reinforcing the significance of completing the full course, even if symptoms start to improve. This practice helps prevent antibiotic resistance and ensures the infection is fully cleared. Key tips include:

• Take cefixime as directed, maintaining consistent timing.
• Do not skip doses; if missed, take as soon as remembered unless it's close to the next dose.
• Store the medication as specified, typically in a cool, dry place away from light.

By following these guidelines, patients can ensure they receive the best outcomes from cefixime treatment while contributing to broader public health goals.

Delivery Times by City

City	Region	Delivery Time
London	Greater London	5–7 days
Birmingham	West Midlands	5–7 days
Manchester	North West	5–7 days
Glasgow	Scotland	5–7 days
Leeds	West Yorkshire	5–7 days
Bristol	South West	5–7 days
Sheffield	South Yorkshire	5–7 days
Newcastle	North East	5–7 days
Cardiff	Wales	5–9 days
Coventry	West Midlands	5–9 days
Norwich	East Anglia	5–9 days
Plymouth	South West	5–9 days
Wolverhampton	West Midlands	5–9 days
Southampton	South East	5–9 days
Brighton	South East	5–9 days