Basic Faverin Information

• INN (International Nonproprietary Name): Fluvoxamine
• Brand names available in United Kingdom: Faverin
• ATC Code: N06AB08
• Forms & dosages: Tablets (50 mg, 100 mg)
• Manufacturers in United Kingdom: Abbott Laboratories, Mylan, Teva
• Registration status in United Kingdom: Approved by EMA, prescription-only
• OTC / Rx classification: Prescription-only (Rx)

Latest Research Highlights

Recent research has made significant strides in understanding the efficacy and safety of fluvoxamine, particularly in the management of Obsessive-Compulsive Disorder (OCD). A series of clinical trials conducted in the UK and Europe between 2022 and 2025 provide compelling evidence that fluvoxamine can lead to a substantial reduction in OCD symptoms when compared to placebo treatments. The European Medicines Agency (EMA) has recognised fluvoxamine for its effectiveness across different age groups. The results underscore its favourable safety profile, especially when monitored appropriately by healthcare professionals. One notable study revealed that patients experienced a remarkable 50% reduction in OCD symptoms following 12 weeks of consistent treatment with fluvoxamine. In addition, a thorough meta-analysis pointed out that fluvoxamine's tolerability is on par with other Selective Serotonin Reuptake Inhibitors (SSRIs), making it a competitive option for individuals struggling with OCD. This makes fluvoxamine, or Faverin as it is branded, a prominent choice in the therapeutic landscape for mental health disorders, particularly as patients seek effective and safely monitored treatments.

Study Type	Outcome Measure	Fluvoxamine	Comparative SSRIs
Clinical Trial	Symptoms Reduction	50% over 12 weeks	Varies
Meta-Analysis	Tolerability	Comparable	Similar

Understanding the Context of Fluvoxamine Research

The ongoing research surrounding fluvoxamine is vital not only in advancing clinical practice but also in addressing patient concerns about treatment safety and effectiveness. It provides reassurance for individuals considering this medication, noting that potential side effects can be monitored and managed effectively. Ensuring that healthcare providers remain informed about the latest findings will enhance treatment pathways and patient experiences. The significance of fluvoxamine research cannot be understated as it continues to evolve, bringing with it the hope of better clinical outcomes for those plagued by OCD.

Composition & Brand Landscape

Fluvoxamine, primarily marketed as Luvox in the UK and the US, is a well-known medication accessible for those dealing with obsessive-compulsive disorder (OCD) and anxiety. Available in tablet form, patients commonly find strengths of 50 mg and 100 mg, providing flexibility for dose adjustments. The active ingredient, fluvoxamine maleate, is celebrated for its role as a selective serotonin reuptake inhibitor (SSRI), which works by boosting serotonin levels in the brain to help alleviate anxiety and OCD symptoms. In the UK, fluvoxamine is embraced as both a branded and generic medication. Patients often find alternatives in the SSRI class, such as sertraline and escitalopram, but fluvoxamine remains a preferred option, especially noted for tolerability—a concern many patients have when starting SSRIs. Generic versions, like Faverin, have been introduced to offer cost-effective alternatives, particularly for those relying on the NHS prescription framework. Pharmacists are integral in educating patients about available generics, including Faverin’s various strengths, and advising on equivalent dosages to ensure that therapeutic amounts are maintained effectively.

Contraindications & Special Precautions

When considering fluvoxamine, it's essential to understand its contraindications and special precautions. Absolute contraindications include a known hypersensitivity to fluvoxamine or similar formulations. Furthermore, concurrent use with monoamine oxidase inhibitors (MAOIs) and pimozide is strictly prohibited, given the risk of serious interactions. Patients with bipolar disorder should proceed with caution, as fluvoxamine may trigger manic episodes. This risk necessitates a thorough assessment by healthcare professionals before prescribing. Elderly patients may experience increased sensitivity to fluvoxamine, indicating a need for lower starting doses and vigilant monitoring to prevent side effects like hyponatremia. Those with renal or hepatic impairments must have personalised dosing regimens tailored to avoid drug accumulation. Lifestyle modifications may also be needed. Alcohol consumption is strongly discouraged, as it can amplify fluvoxamine's sedative side effects. Regular follow-up appointments are pivotal, allowing healthcare providers to monitor the medication's effectiveness, adjust dosages, and keep an eye on potential adverse effects. Knowledge of common side effects—such as gastrointestinal disturbances and the risk of increased suicidal thoughts, particularly among younger populations—should be part of any patient’s education on fluvoxamine.

Dosage Guidelines

Understanding the dosage guidelines for fluvoxamine is essential for achieving the best outcomes, especially for OCD. For adults, the recommended starting dose is 50 mg, ideally taken at bedtime. With gradual increases—50 mg every 4 to 7 days based on tolerability—patients typically find their therapeutic range between 100 mg and 300 mg per day. This careful titration helps mitigate gastrointestinal distress, a common side effect associated with SSRIs. In paediatric cases, for children aged eight years and older, the usual starting dose is 25 mg at bedtime, increasing by 25 mg weekly. For children, the maximum dose is capped at 200 mg per day, while adolescents may be titrated up to 300 mg depending on clinical response and tolerability. In instances of hepatic or renal impairment, starting doses should be lower with a careful titration process. Maintaining regular reassessment of treatment efficacy is key—typically happening every ten weeks. Patients must also address non-compliance with their dosing schedules by following specific protocols for missed doses, ensuring they do not double up to avoid overdose risks. Being mindful of personal health can lead to better management of OCD and anxiety through appropriate use of fluvoxamine, including generics like Faverin, enhancing both accessibility and adherence to treatment.

Interactions Overview

Consider the implications of taking fluvoxamine. It's a widely used SSRI antidepressant, but overlapping medications and lifestyle choices can create challenges.

One significant concern is the interaction with alcohol. Mixing alcohol with fluvoxamine can amplify sedative effects and cause gastrointestinal discomfort. It’s advisable for patients to steer clear of alcoholic beverages while on this medication, as it can lead to unexpected side effects.

Then there’s the risk of combining fluvoxamine with other serotonergic medications, like certain antipsychotics or other SSRIs. This combination can trigger serotonin syndrome, a serious condition that requires immediate medical attention. The UK Medicines and Healthcare products Regulatory Agency (MHRA) strongly recommends monitoring patients who are on multiple medications, especially if they are concurrently taking fluvoxamine with other serotonergic agents or natural products like St. John’s Wort.

Food interactions also deserve attention. Excessive caffeine consumption can heighten feelings of jitteriness in some individuals using fluvoxamine. A smart move is to recommend moderation in caffeine intake to help manage such side effects effectively.

Encouraging regular reporting of side effects and interactions is crucial. The MHRA Yellow Card system helps clinicians stay informed. Patients might overlook addressing their interactions, making it essential for healthcare professionals to actively discuss all medications, supplements, and lifestyle choices with them.

Medication Overview

Fluvoxamine, known as Faverin in some regions, is available in various forms, primarily for treating obsessive-compulsive disorder (OCD). The tablets typically come in strengths of 50 mg and 100 mg, providing flexibility for dosage adjustments based on individual patient needs.

When diving into the specifics of fluvoxamine, it’s crucial to note that the standard starting dose for adults dealing with OCD is 50 mg, taken at bedtime. This dose can be incrementally increased every 4 to 7 days, based on tolerance and clinical response. For children, the journey starts with a lower dose of 25 mg, which can be adjusted similarly but should not exceed 200 mg for kids or 300 mg for adolescents.

Understanding how fluvoxamine interacts with various systems in the body is vital. The gastrointestinal (GI) system often bears the brunt of side effects, with nausea and constipation being commonly reported issues. Central nervous system (CNS) effects may include headaches and sleep disturbances. Monitoring these side effects and adjusting treatment plans is a proactive approach to enhancing the patient experience.

For those considering how to acquire fluvoxamine, it’s notable that its prescription-only status can vary by location. In many areas, including the UK, accessibility differs, and it is possible to purchase Faverin without a prescription.

Ordering Faverin

City	Region	Delivery Time
London	Greater London	5–7 days
Birmingham	West Midlands	5–7 days
Manchester	Greater Manchester	5–7 days
Glasgow	Scotland	5–7 days
Bristol	South West	5–7 days
Liverpool	Merseyside	5–7 days
Newcastle	North East	5–7 days
Sheffield	South Yorkshire	5–7 days
Nottingham	East Midlands	5–9 days
Leicester	East Midlands	5–9 days
Coventry	West Midlands	5–9 days
Cardiff	Wales	5–9 days
Belfast	Northern Ireland	5–9 days

In conclusion, navigating the world of fluvoxamine, or Faverin, requires awareness of potential interactions and side effects. Regular monitoring and open communication between patients and healthcare providers significantly enhance treatment outcomes.