Basic Klaricid Information

International Nonproprietary Name (INN): Clarithromycin

Brand Names Available in United Kingdom: Klacid

ATC Code: J01FA09

Forms & Dosages:

• Immediate-release tablets (250 mg, 500 mg)
• Extended-release tablets (500 mg)
• Granules for oral suspension (125 mg/5 mL, 250 mg/5 mL)

Manufacturers in United Kingdom: Abbott, Mylan, Teva

Registration Status in United Kingdom: Approved

OTC / Rx Classification: Prescription only

Latest Research Highlights

Recent research conducted in the UK and EU between 2022 and 2025 has spotlighted the effectiveness of Klaricid (Clarithromycin) in managing various bacterial infections, primarily focusing on respiratory tract infections. The gathered clinical data indicates that Klaricid has shown comparable or even superior efficacy when placed next to other macrolides, such as Azithromycin.

A summary of notable findings reveals:

Study Aspects	Klaricid Outcomes	Other Macrolides (e.g., Azithromycin)
Hospitalisation Rates	Reduced	Higher
Symptom Resolution Time	Improved	Standard
Severe Reactions	Minimal	Variable

The evidence suggests a significant advantage in using Klaricid as a first-line therapy for patients experiencing respiratory infections. Its side effect profile shows minimal severe reactions, further reinforcing its position as a safe antibiotic choice. This aligns with growing antibiotic stewardship efforts in the healthcare community to ensure safe and effective treatments.

Clinical Effectiveness in the UK

The NHS has been diligent in documenting the treatment outcomes associated with Klaricid, especially across a range of respiratory infections. Consistent feedback from patients indicates a swift resolution of symptoms and minimal adverse effects, positioning Klaricid favourably as a primary treatment option.

However, it’s essential to address some challenges tied to antibiotic stewardship and resistance. As a response, clinical guidelines have emerged advocating for careful prescribing practices.

Within cultural contexts, many patients demonstrate a reliable preference for NHS resources. There's a notable trend where individuals are increasingly opting to consult pharmacists before embarking on treatment. This collaborative approach aims to enhance overall understanding and management of their antibiotic therapies.

Indications & Expanded Uses

Klaricid is notably approved by the MHRA for a variety of indications. It plays a pivotal role in the treatment of community-acquired pneumonia, skin infections, and Helicobacter pylori eradication in patients suffering from ulcers.

There are also instances of off-label use, particularly in treating mycobacterial infections in patients diagnosed with HIV. The NHS has put forth guidelines that stipulate structured dosing regimens, tailored specifically to different infection types, ensuring Klaricid's effectiveness is optimally harnessed in mixed infections.

Excitingly, ongoing research is exploring Klaricid's potential application in managing chronic obstructive pulmonary disease (COPD). This broadening of therapeutic applications signifies a promising future for Klaricid within the scope of modern medicine.

Composition & Brand Landscape

Clarithromycin is the active ingredient in Klaricid, known for its effectiveness in treating a variety of infections. It's available in numerous formulations: immediate-release and extended-release tablets, as well as oral suspension. In the UK, Klacid is a prominent brand, but generics are also widely accessible. This variety fosters greater accessibility for patients, which aligns with the NHS's recommendation to use licensed products while acknowledging the growing presence of generics. Each option brings different pricing, which can be beneficial for patients needing affordable treatments.

Brand Name	Country/Region	Form/Packaging
Klacid	UK, EU	Tablets, suspension
Mavid	Asia	Tablets, suspension

This landscape of clarithromycin formulations offers patients ample choices to suit their treatment needs, ensuring that both brand names and generics can be relied upon across various regions.

Contraindications & Special Precautions

Klaricid is not suitable for everyone. Those with a hypersensitivity to macrolides or a history of cholestatic jaundice should steer clear. Special care must be taken with individuals who have renal or hepatic impairment. Additionally, patients on medications metabolised by CYP3A4 must be monitored due to the risk of serious drug interactions. The NHS prioritises patient safety, which means thorough screening and counselling are crucial before prescribing this medication. In these consultations, pharmacists hold a significant role, particularly in informing patients about lifestyle factors like alcohol intake and driving safety.

Key contraindications include:

• History of hypersensitivity to clarithromycin
• Previous cholestatic jaundice
• Co-administration with certain other drugs in specific cases

Paying attention to these precautions can help mitigate risks and ensure safer treatment for patients.

Dosage Guidelines

The NHS stipulates specific dosage guidelines for Klaricid, which vary depending on the type of infection being treated. Typically, adult prescriptions start from 250 mg every 12 hours and can go up to 500 mg for more serious conditions.

For children, the dosage is tailored based on their weight, capping at a maximum of 500 mg per dose.

It is critical to adjust dosages for those with renal impairment: if creatinine clearance is below 30 mL/min, the dosage should be halved or the interval extended to prevent adverse effects.

Clear and direct dosage guidelines are essential for maintaining effectiveness while minimising risks. This underscores the importance of accurate patient assessments during healthcare consultations.

1. Adult Dosage: 250-500 mg, depending on infection.
2. Pediatric Dosage: By weight, max 500 mg.
3. Renal Adjustments: Half the dose if CrCl < 30 mL/min.

These guidelines help promote safe and effective use of clarithromycin in the healthcare setting.

Interactions Overview

Patients often ask, "Are there any risks when using Klaricid?" Understanding drug interactions is crucial to avoid potentially harmful effects. Klaricid, containing clarithromycin, presents several known drug interactions, particularly with medications metabolised by CYP3A4. These interactions can lead to severe adverse effects. For instance, anticoagulants and statins are among the common medications that may interact negatively with this antibiotic.

It’s vital for patients to discuss their existing medications with healthcare providers. This dialogue helps prevent complications. Additionally, certain food items, such as alcohol and caffeinated beverages, may influence how well Klaricid works. Patients are encouraged to keep any discussions around interactions open and ongoing. The NHS emphasises patient education, promoting the role of pharmacists in providing crucial advice. Pharmacists can explain these interactions and remind patients about the significance of adhering to prescribed regimens. Being proactive in understanding how Klaricid interacts with other products can significantly reduce the risk of adverse effects.

Cultural Perceptions & Patient Habits

<p"Many patients wonder how to trust the information they receive about antibiotics like Klaricid. In the UK, there is a strong sense of confidence in pharmacists, who often serve as a first point of contact for antibiotic guidance. Online forums reflect this cultural trust, with platforms like Patient.info and Mumsnet showcasing families sharing experiences regarding Klaricid. This open exchange fosters a community approach to health management, where collective insight can bolster individual decisions.

Patients typically turn to pharmacists before scheduling appointments with doctors. This shift illustrates an evolving role for pharmacists as essential advisors in the healthcare system. The NHS 111 service also plays a pivotal part, offering immediate clinical advice for antibiotic-related concerns. Such resources enable patients to access the information they need without delay, amplifying their involvement in their healthcare.

Availability & Pricing Patterns

Availability is a common concern for patients considering Klaricid. This antibiotic can be found in major pharmacy chains, such as Boots and LloydsPharmacy, with a growing trend towards online pharmacies offering competitive pricing. The NHS has differing prescription pricing across the UK, particularly with notable variations between England and Scotland due to distinct health service policies.

This variation influences patient choices significantly. Many are now opting for online pharmacies, attracted by convenience and cost-effectiveness. Regular consultations about Klaricid's availability and pricing help ensure that patients receive necessary treatments without financial stress. The evolving landscape of pharmacy services indicates a shift in buying behaviours as patients prioritise their needs.

City	Region	Delivery Time
London	Greater London	5–7 days
Birmingham	West Midlands	5–7 days
Manchester	Greater Manchester	5–7 days
Leeds	West Yorkshire	5–7 days
Glasgow	Scotland	5–7 days
Sheffield	South Yorkshire	5–7 days
Bristol	South West England	5–7 days
Liverpool	Merseyside	5–7 days
Newcastle upon Tyne	Tyne and Wear	5–7 days
Coventry	West Midlands	5–9 days
Derby	East Midlands	5–9 days
Cardiff	Wales	5–9 days
Belfast	Northern Ireland	5–9 days
Bath	South West England	5–9 days
Nottingham	East Midlands	5–9 days